– Dr. Bill Smythe
Family & cosmetic dentistry in Louisville, KY — same Dixie Highway location since 1973. Accepting new patients of all ages.
Welcome
At the office of Dr. William H. Smythe DMD, your dentist in Louisville, we are committed to giving you a beautiful and healthy smile. Our expert skills and compassionate care, coupled with the latest advances in dental technology, make every visit to our practice a positive, comfortable, and stress-free experience.
Proudly serving the Louisville community and the surrounding areas since 1973, our office has established a reputation of excellence based on the quality of patient care that we provide and the successful treatment outcomes that we achieve.
In our office, every patient is treated with the individualized care and attention that they deserve. We take the time to listen to your smile goals, assess your dental needs, and develop the best treatment plan.
Meet Our Team
Why Choose Us?
Dr. Smythe and the entire dental team invite you to schedule an appointment to see why so many patients love our office.
State-of-the-Art Dental Office
Multi Specialty Under One Roof
25 Years of Experience
Same Location Since 1973
Advanced Infection Control
Comfortable Injections
A Team You Can Trust
Our experienced dental team has been working together for more than a decade, providing consistent, high-quality care to families throughout Louisville. Patients see the same friendly faces visit after visit, year after year.
Long-tenured staff means our hygienists, assistants, and front-office team know you, your history, and your preferences — the kind of personalized attention you only get from a stable, family-run practice.
Meet The Team Meet Your Dentist
Dr. William H. Smythe IV graduated from the University of Louisville School of Dentistry in 1996 and has practiced from the same Dixie Highway office since — the office his father, Dr. Bill Sr., opened in 1973. Three generations of the Smythe family have cared for South End Louisville patients from this location.
Dr. Smythe practices general and cosmetic dentistry, with treatment plans built around what each patient actually wants for their smile rather than a one-size-fits-all approach. New patients are welcome, and most insurance plans are accepted.
Medically reviewed by Dr. William H. Smythe IV, DMD · University of Louisville School of Dentistry, 1996 · Kentucky dental license #3628.
Read Full Bio & Meet The TeamFrom the Blog
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Read More →What Our Patients Are Saying
Killian Trusty
5 months ago
“Doctor Smythe's office has easily been the best dental experiences I've ever had. The staff are very pleasant and actually listen to my concerns and are very patient. I came to them with absolutely awful teeth that I was very self-conscious about due to bad habits and a very profound fear of needles and injections. They have been very compassionate and realistic with me and I can happily recommend them to anyone that asks.”
Theresa Endler
5 months ago
“I was very pleased with my first visit to Dr Smythe’s office. The staff was very friendly. My hygienist, Jenny explained everything that she was doing and why. Dr Smythe was fantastic. I highly recommend this office!”
Jessica Stringer
5 months ago
“I am a new patient and they are awesome. Everyone was so friendly and easy to talk to. They gave me good information on helping my teeth and gums. I'm glad I chose them as my new dental office.”
Cindy F
5 months ago
“I had to leave my dentist that I had been going to for YEARS. I decided to try Dr. William Smythe on Dixie Hwy. They were all so friendly and made me feel like I had been going there for years. So glad I decided to give them a chance. 😊”
Common Questions
Yes — William H. Smythe DMD is currently accepting new patients of all ages. The practice has cared for Louisville families from the same Dixie Highway location since 1973. To schedule a first visit, request an appointment online or call (502) 448-2876.
We accept most dental insurance plans and file claims on your behalf, so patients do not have to chase reimbursement themselves. Bring your insurance card to your first visit and the front office will verify benefits before treatment.
We accept Mastercard, Visa, American Express, Discover, cash, and CareCredit financing. CareCredit lets patients spread larger treatment costs across monthly payments.
The office is at 5141 Dixie Highway, Suite 202, Louisville, KY 40216 — same location since 1973. Free on-site parking is available. The building has a wheelchair ramp and an elevator to the second-floor Suite 202 office.
Monday through Wednesday: 9 AM to 4 PM. Thursday: 9 AM to 2 PM. Friday: 8:30 AM to 12:30 PM. Closed Saturday and Sunday.
Schedule your visit with Dr. Bill Smythe today.
