“Nobody Cares How Much You Know, Until They Know How Much You Care.”
– Dr. Bill Smythe
Family & cosmetic dentistry in Louisville, KY — same Dixie Highway location since 1973. Accepting new patients of all ages.
- 1973 Same location since 1973
- 3 generations Family-run dental practice
- All ages Accepting new patients
- Most insurance We file claims for you
- Free parking On-site, ramp & elevator
- Dixie Hwy 5141 Dixie Hwy, Ste 202
Welcome
A Louisville Dentist serving families since 1973
At the office of Dr. William H. Smythe DMD, your dentist in Louisville, we are committed to giving you a beautiful and healthy smile. Our expert skills and compassionate care, coupled with the latest advances in dental technology, make every visit to our practice a positive, comfortable, and stress-free experience.
Proudly serving the Louisville community and the surrounding areas since 1973, our office has established a reputation of excellence based on the quality of patient care that we provide and the successful treatment outcomes that we achieve.
In our office, every patient is treated with the individualized care and attention that they deserve. We take the time to listen to your smile goals, assess your dental needs, and develop the best treatment plan.
Meet Our Team
Why Choose Us?
Why Patients Love Our Office
Dr. Smythe and the entire dental team invite you to schedule an appointment to see why so many patients love our office.
State-of-the-Art Dental Office
Multi Specialty Under One Roof
25 Years of Experience
Same Location Since 1973
Advanced Infection Control
Comfortable Injections
A Team You Can Trust
Together Over 10 Years!
Our experienced dental team has been working together for more than a decade, providing consistent, high-quality care to families throughout Louisville. Patients see the same friendly faces visit after visit, year after year.
Long-tenured staff means our hygienists, assistants, and front-office team know you, your history, and your preferences — the kind of personalized attention you only get from a stable, family-run practice.
Meet The Team Meet Your Dentist
Dr. William H. Smythe IV, DMD
Dr. William H. Smythe IV graduated from the University of Louisville School of Dentistry in 1996 and has practiced from the same Dixie Highway office since — the office his father, Dr. Bill Sr., opened in 1973. Three generations of the Smythe family have cared for South End Louisville patients from this location.
Dr. Smythe practices general and cosmetic dentistry, with treatment plans built around what each patient actually wants for their smile rather than a one-size-fits-all approach. New patients are welcome, and most insurance plans are accepted.
Medically reviewed by Dr. William H. Smythe IV, DMD · University of Louisville School of Dentistry, 1996 · Kentucky dental license #7195.
Read Full Bio & Meet The Team
What Makes Us Different
Our three key pillars
We are a patient-focused, private dental practice dedicated to providing high-quality care with a personal touch. Our practice distinguishes itself through three key pillars: specialized cosmetic dentistry, same-day emergency appointments for urgent relief, and flexible payment options that make high-quality care accessible to all of our patients.
- Specialized cosmetic dentistry
- Same-day emergency appointments for urgent relief
- Flexible payment options that make high-quality care accessible to all of our patients
What We Do
Featured Services
These are the treatments Dr. Smythe’s practice is built around — from a single crown to a full-mouth restoration, planned and placed in the same Dixie Highway office the family has run since 1973.
Dental Implants Learn More 
All-on-4 Implants Learn More 
Dentures Learn More 
Porcelain Veneers Learn More 
Smile Makeover Learn More 
Full-Mouth Restoration Learn More 
Teeth Whitening Learn More 
SureSmile Clear Aligners Learn More 
Crowns & Bridges Learn More 
Same-Day Emergency Care Learn More 
Pediatric Dentistry Learn More Technology
The equipment we treat with
Our expert skills and compassionate care, coupled with the latest advances in dental technology, make every visit to our practice a positive, comfortable, and stress-free experience.
- Digital impressions
- Laser treatments
- Zoom laser same-day bleaching
- Digital X-rays
Your Comfort
You set the pace of the appointment
We prioritize patient comfort by offering relaxation options, and we are committed to a patient-centered approach that includes taking breaks at any time during treatment to ensure a stress-free experience.
Insurance & Financing
Most PPO plans accepted — and we file for you
Flexible payment options make high-quality care accessible to all of our patients, so cost is never the reason treatment gets put off.
Plans we accept
- Delta Dental PPO Plus Premier
- Aetna PPO
- Cigna
- MetLife
- BCBS
- Guardian
- United Healthcare
Plus others that are not listed — call (502) 448-2876 and we will check your plan for you.
Payment options
- CareCredit
- Cherry
From the Blog
Our Dental Blog
Enhance Your Teeth Whitening Results
There is no quicker or easier way to dramatically improve the look of your smile than professional teeth whitening...
Read More →Everyday Things That Are Staining Your Teeth
Having a bright smile is a sign of good health, and it not only makes your face more attractive...
Read More →Is Denture Treatment Right for You?
If you have lost all of your teeth or just a few, you are probably a candidate for some form of denture treatment...
Read More →The Advantages of Hybrid Dentures
Hybrid dentures combine the security of dental implants with the affordability of traditional dentures...
Read More →What Our Patients Are Saying
Loved by Louisville Patients
Killian Trusty
5 months ago
“Doctor Smythe's office has easily been the best dental experiences I've ever had. The staff are very pleasant and actually listen to my concerns and are very patient. I came to them with absolutely awful teeth that I was very self-conscious about due to bad habits and a very profound fear of needles and injections. They have been very compassionate and realistic with me and I can happily recommend them to anyone that asks.”
Theresa Endler
5 months ago
“I was very pleased with my first visit to Dr Smythe’s office. The staff was very friendly. My hygienist, Jenny explained everything that she was doing and why. Dr Smythe was fantastic. I highly recommend this office!”
Jessica Stringer
5 months ago
“I am a new patient and they are awesome. Everyone was so friendly and easy to talk to. They gave me good information on helping my teeth and gums. I'm glad I chose them as my new dental office.”
Cindy F
5 months ago
“I had to leave my dentist that I had been going to for YEARS. I decided to try Dr. William Smythe on Dixie Hwy. They were all so friendly and made me feel like I had been going there for years. So glad I decided to give them a chance. 😊”
Where Our Patients Come From
Serving Louisville and the surrounding communities
- Valley Station
- Pleasure Ridge Park
- Shively
- Radcliff
- Brandenburg
- Ft. Knox
- West Point
Common Questions
Frequently Asked Questions
Are you accepting new patients in Louisville?
Yes — William H. Smythe DMD is currently accepting new patients of all ages. The practice has cared for Louisville families from the same Dixie Highway location since 1973. To schedule a first visit, request an appointment online or call (502) 448-2876.
What insurance do you accept?
We accept most dental insurance plans and file claims on your behalf, so patients do not have to chase reimbursement themselves. Bring your insurance card to your first visit and the front office will verify benefits before treatment.
What payment methods do you accept?
We accept Mastercard, Visa, American Express, Discover, cash, and CareCredit financing. CareCredit lets patients spread larger treatment costs across monthly payments.
Where is the office located and is parking available?
The office is at 5141 Dixie Highway, Suite 202, Louisville, KY 40216 — same location since 1973. Free on-site parking is available. The building has a wheelchair ramp and an elevator to the second-floor Suite 202 office.
What are your office hours?
Monday through Wednesday: 9 AM to 4 PM. Thursday: 9 AM to 2 PM. Friday: 8:30 AM to 12:30 PM. Closed Saturday and Sunday.
Same location since 1973. Accepting new patients.
Schedule your visit with Dr. Bill Smythe today.